1. Clinical predictors of the hypoglycemic effect of sodium-glucose co-transporter-2 inhibitors in hyperuricemic patients: a retrospective descriptive observational study
    Hirai T, Kawagoe Y, Kei M, Ogawa R, Itoh T.
    Biol Pharm Bull., in press.
  2. Serum digoxin concentrations and outcomes in patients with heart failure and atrial fibrillation: a single-center observational study
    Hirai T, Naganuma M, Shiga T, Echizen H, Itoh T, Hagiwara N.
    Jpn J Clin Pharmacol Ther., in press.
  3. Effects of overweight and underweight on the treatment outcomes of rheumatoid arthritis patients treated with biological drugs: a retrospective observational descriptive study
    Hirai T, Funaki A, Murakami K, Hanada K, Itoh T.
    J Clin Pharm Ther., in press.


  1. Risk factors for vancomycin nephrotoxicity and time course of renal function during vancomycin treatment
    Hirai T, Hanada K, Kanno A, Akashi M, Itoh T.
    Eur J Clin Pharmacol. 2019;75:859-866.
  2. Renin-angiotensin system inhibitors for countering proteinuria induced by angiogenesis inhibitors: a retrospective observational analysis
    Hirai T, Shuji Y, Takiyama M, Hanada K, Itoh T.
    Cancer Chemother Pharmacol. 2019;84:195-202.
  3. Relationship between Recurrent Falls and Medication Use during Acute-Care Hospitalization: A Retrospective Descriptive Study
    Hirai T, Ishikawa Y, Kawagoe Y, Ogawa Y, Ogawa R, Itoh T.
    Biol Pharm Bull. 2019;42:1192-1198.


  1. Low body mass index is a risk factor for hyperkalaemia associated with angiotensin converting enzyme inhibitors and angiotensin II receptor blockers treatments.
    Hirai T, Yamaga R, Fujita A, Itoh T.
    J Clin Pharm Ther. 2018;43:829-835.
  2. Evaluation of a pharmacokinetic-pharmacodynamic model for hypouricaemic effects of febuxostat using datasets obtained from real-world patients
    Hirai T, Itoh T, Kimura T, Echizen H.
    Br J Clin Pharmacol. 2018;84:2260-2269.
  3. Impact of relative dose intensity on bone marrow suppression induced by S-1: retrospective observational study
    Hirai T, Ogawa R, Yamaga R, Itoh T.
    J Pharm Health Care Sci. 2018;4:30.